Toxicology & Therapeutic Drug Monitoring

Parameter Age Toxic Level Units
Acetaminophen >150            (۴ hours after dose)

>40            (۱۲ hours after dose)

μg/mL
Carbamazepine >15 μg/mL
Dogoxin >3

(Non-cardiac symptoms such as tiredness, muscle weakness, nausea, vomiting, lethargy, and

headache and cardiac symptoms such as sinus arrhythmia, bradycardia, and various degrees of AV block)

ng/ml
Ethanol >65 mmol/L
Ethosuximide >150 μg/mL
Lead, Blood (۰-۱۵ yrs)

(≥۱۶ yrs)

≥۴۵

≥۷۰

μg/dL
Lead, Urine ≥۱۰۰۰ μg/L
Lithium >2 mEq/L
Methanol Any value detected mg/dL
Phenobarbital (۰ -۳ months)

(۳ months-adult)

>35

>40

μg/mL
Phenylalanin (New born)

(Pediatric)

>205

>100

µmol/L
Phenytoin, Free >3 μg/mL
Phenytoin (Dilantin), Total (۰ -۳ months)

(۳ months-adult)

>14

>30

Primidone >15 μg/mL
Salicylate(Aspirin) >30 mg/dL
Valporic Acid(VPA), Total >150 μg/mL

 

References

  1. ARUP Laboratories
  2. Stanford Anatomic Pathology & Clinical Laboratories
  3. Mayo Medical Laboratories
  4. Department of LABORATORY MEDICINE, University of Washington.
  5. Thomas L. Critical limits of laboratory results for urgent clinician notification. EJIFCC. 2003;14:1-8.
  6. Emancipator K. Critical values: ASCP practice parameter. American journal of clinical pathology. 1997 Sep 1;108(3):247-53.
  7. McFarlane A, Aslan B, Raby A, Bourner G, Padmore R. Critical values in Hematology. International journal of laboratory hematology. 2015 Feb 1;37(1):36-43.

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